5/12/2025
Last update
5/12/2025
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.3
USERS' SCORE
Moderately Good
Based on 38 Reviews
7
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Selenium (from SelenoExcell® High Selenium Yeast) (Saccharomyces cerevisiae)
50 mcg
90%
Molybdenum (from molybdenum glycinate chelate)
50 mcg
110%
N-Acetylcysteine (NAC)
600 mg
†
Top Medical Research Studies
9
Selenium aids Graves' orbitopathy treatment
We explored how selenium supplementation might help individuals suffering from Graves' orbitopathy, an autoimmune disorder linked to thyroid dysfunction. Our approach involved a systematic review and meta-analysis that assessed results from four randomized controlled trials.
The findings revealed that selenium supplementation had a significant positive impact on various aspects of Graves' orbitopathy. Over a period of six months, patients taking selenium showed a notable reduction in clinical activity scores, which reflect the severity of eye symptoms. Furthermore, their quality of life also improved significantly.
We observed improvements not only in the overall quality of life specific to eye conditions, but also in visual and psychological functioning scores. Additionally, selenium appeared to reduce the width of the eyelids, providing further benefits for eye-related symptoms. However, we found no significant changes in other areas, such as eye bulging or muscle movement abilities.
Importantly, selenium supplementation was deemed safe with minor side effects reported, suggesting it could be a viable option for managing Graves' orbitopathy. While our results are promising, we believe further research is needed to thoroughly validate the long-term effectiveness and safety of selenium treatment for this condition.
The findings revealed that selenium supplementation had a significant positive impact on various aspects of Graves' orbitopathy. Over a period of six months, patients taking selenium showed a notable reduction in clinical activity scores, which reflect the severity of eye symptoms. Furthermore, their quality of life also improved significantly.
We observed improvements not only in the overall quality of life specific to eye conditions, but also in visual and psychological functioning scores. Additionally, selenium appeared to reduce the width of the eyelids, providing further benefits for eye-related symptoms. However, we found no significant changes in other areas, such as eye bulging or muscle movement abilities.
Importantly, selenium supplementation was deemed safe with minor side effects reported, suggesting it could be a viable option for managing Graves' orbitopathy. While our results are promising, we believe further research is needed to thoroughly validate the long-term effectiveness and safety of selenium treatment for this condition.
Read More
0
We aimed to explore how selenium affects autoimmune thyroid disease (AITD), specifically looking at three conditions: autoimmune thyroiditis (AIT), autoimmune hyperthyroidism (AIH), and Graves' disease (GD). Using a research method called Mendelian randomization, we analyzed genetic data to establish potential causal links between selenium levels and these autoimmune disorders.
Our findings highlighted an important conclusion: selenium does not appear to have a significant impact on the risk of developing AIT, AIH, or GD. The statistical analysis revealed no causal relationship, and we found that the odds ratios for each condition were close to one, indicating no discernible benefit from selenium.
Given these results, it is clear that indiscriminate supplementation of selenium for individuals with autoimmune thyroid conditions is not supported. Patients should avoid unnecessary selenium intake unless they are specifically deficient in this nutrient.
Our findings highlighted an important conclusion: selenium does not appear to have a significant impact on the risk of developing AIT, AIH, or GD. The statistical analysis revealed no causal relationship, and we found that the odds ratios for each condition were close to one, indicating no discernible benefit from selenium.
Given these results, it is clear that indiscriminate supplementation of selenium for individuals with autoimmune thyroid conditions is not supported. Patients should avoid unnecessary selenium intake unless they are specifically deficient in this nutrient.
Read More
9
We explored the effects of selenium supplements on patients with Hashimoto's thyroiditis, an autoimmune disorder that can affect thyroid function. Through a structured analysis of studies, we focused on how selenium could potentially lower the levels of thyroid autoantibodies.
Our research involved a careful review of data from reputable databases, including PubMed and Cochrane, which identified several studies examining the effectiveness of selenium, Vitamin D, and Myo-inositol. Among these, the results showed that selenium supplementation significantly reduced both thyroid peroxidase autoantibodies (TPOAb) and thyroglobulin autoantibodies (TgAb) when compared to a placebo group.
Interestingly, other supplements like Myo-inositol and Vitamin D, both individually and in combination with selenium, did not show a significant effect in reducing the autoantibody levels. Based on these findings, it appears that incorporating selenium into treatment regimens may offer a beneficial adjunct for those managing Hashimoto's thyroiditis.
Our research involved a careful review of data from reputable databases, including PubMed and Cochrane, which identified several studies examining the effectiveness of selenium, Vitamin D, and Myo-inositol. Among these, the results showed that selenium supplementation significantly reduced both thyroid peroxidase autoantibodies (TPOAb) and thyroglobulin autoantibodies (TgAb) when compared to a placebo group.
Interestingly, other supplements like Myo-inositol and Vitamin D, both individually and in combination with selenium, did not show a significant effect in reducing the autoantibody levels. Based on these findings, it appears that incorporating selenium into treatment regimens may offer a beneficial adjunct for those managing Hashimoto's thyroiditis.
Read More
Most Useful Reviews
9
Easier breathing
28 people found this helpful
Autoimmune disorder! I purchased this product at a great price. The small package fits in the palm of my hand and the quality appears satisfactory, with selenium and molybdenum in the ingredients. The capsules are of average size and easy to swallow. While the smell isn't pleasant, I believe it's due to the selenium. It effectively liquefies biofilms, mucus, and other pathogens, gently ridding the body of them. It strengthens my immune system, preventing illness at the first signs of trouble. After experiencing terrible shortness of breath due to my autoimmune disorder, this drug has significantly improved my ability to breathe! I highly recommend it!
Read More
8
Detoxification support
26 people found this helpful
N-acetylcysteine is an effective detoxification regulator that supports glutathione production, vital for eliminating toxins and maintaining a robust immune system. It helps combat free radicals, which, when accumulated, compromise immunity. This additive, rich in selenium and gluten-free, is remarkable, and I recommend it for overall well-being.
Read More
9
Reduced thyroid antibodies
8 people found this helpful
Initially, I thought NAC was for colds until I was recommended it for my autoimmune disorder (AIT). This supplement made it onto my treatment list. Glutathione deficiency correlates with raised thyroid antibodies. N-acetylcysteine converts to glutathione, helping to reduce those antibodies by neutralising hydrogen peroxide and supporting intestinal permeability and detoxification. I take three capsules (1800 mg) each morning with meals. I've been treatment for under a month, and my antibodies are starting to decrease!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.3
- All Researches
9
We explored a novel oral drug delivery system designed specifically for treating IgA nephropathy, an autoimmune disorder. Using hydroxychloroquine and dexamethasone paired with yeast cell walls, we aimed for targeted delivery to the ileal region.
Our findings revealed that this system effectively reduced harmful IgA levels and improved kidney tissue health in test subjects. We also noted significant reductions in inflammatory markers, suggesting potential benefits in managing IgA nephropathy through this innovative approach.
Our findings revealed that this system effectively reduced harmful IgA levels and improved kidney tissue health in test subjects. We also noted significant reductions in inflammatory markers, suggesting potential benefits in managing IgA nephropathy through this innovative approach.
Read More
9
We investigated the role of certain yeast polysaccharides in modulating immune responses related to autoimmune disorders. Our focus was on mannan/β-1,6-glucan-containing polysaccharides (MGCP), which showed strong anti-inflammatory properties.
MGCP prompted the development of regulatory T cells and reduced harmful immune responses in models of inflammatory diseases. While we saw promising results in laboratory settings, these findings emphasize the potential of using yeast-derived compounds for therapeutic approaches in treating autoimmune conditions.
MGCP prompted the development of regulatory T cells and reduced harmful immune responses in models of inflammatory diseases. While we saw promising results in laboratory settings, these findings emphasize the potential of using yeast-derived compounds for therapeutic approaches in treating autoimmune conditions.
Read More
9
We investigated the effects of a novel treatment targeting BAMBI, a protein involved in immune cell regulation, on autoimmune disorders like psoriasis and arthritis in mice. Through careful experimentation with control groups, we found that the anti-BAMBI antibody significantly increased protective Treg cells and reduced disease progression in various models. This treatment effectively prevented skin psoriasis and type II collagen-induced arthritis, hinting at new therapeutic possibilities for chronic inflammatory conditions driven by immune system dysfunction.
Read More
9
We explored the effects of selenium supplements on patients with Hashimoto's thyroiditis, an autoimmune disorder that can affect thyroid function. Through a structured analysis of studies, we focused on how selenium could potentially lower the levels of thyroid autoantibodies.
Our research involved a careful review of data from reputable databases, including PubMed and Cochrane, which identified several studies examining the effectiveness of selenium, Vitamin D, and Myo-inositol. Among these, the results showed that selenium supplementation significantly reduced both thyroid peroxidase autoantibodies (TPOAb) and thyroglobulin autoantibodies (TgAb) when compared to a placebo group.
Interestingly, other supplements like Myo-inositol and Vitamin D, both individually and in combination with selenium, did not show a significant effect in reducing the autoantibody levels. Based on these findings, it appears that incorporating selenium into treatment regimens may offer a beneficial adjunct for those managing Hashimoto's thyroiditis.
Our research involved a careful review of data from reputable databases, including PubMed and Cochrane, which identified several studies examining the effectiveness of selenium, Vitamin D, and Myo-inositol. Among these, the results showed that selenium supplementation significantly reduced both thyroid peroxidase autoantibodies (TPOAb) and thyroglobulin autoantibodies (TgAb) when compared to a placebo group.
Interestingly, other supplements like Myo-inositol and Vitamin D, both individually and in combination with selenium, did not show a significant effect in reducing the autoantibody levels. Based on these findings, it appears that incorporating selenium into treatment regimens may offer a beneficial adjunct for those managing Hashimoto's thyroiditis.
Read More
9
Selenium aids Graves' orbitopathy treatment
We explored how selenium supplementation might help individuals suffering from Graves' orbitopathy, an autoimmune disorder linked to thyroid dysfunction. Our approach involved a systematic review and meta-analysis that assessed results from four randomized controlled trials.
The findings revealed that selenium supplementation had a significant positive impact on various aspects of Graves' orbitopathy. Over a period of six months, patients taking selenium showed a notable reduction in clinical activity scores, which reflect the severity of eye symptoms. Furthermore, their quality of life also improved significantly.
We observed improvements not only in the overall quality of life specific to eye conditions, but also in visual and psychological functioning scores. Additionally, selenium appeared to reduce the width of the eyelids, providing further benefits for eye-related symptoms. However, we found no significant changes in other areas, such as eye bulging or muscle movement abilities.
Importantly, selenium supplementation was deemed safe with minor side effects reported, suggesting it could be a viable option for managing Graves' orbitopathy. While our results are promising, we believe further research is needed to thoroughly validate the long-term effectiveness and safety of selenium treatment for this condition.
The findings revealed that selenium supplementation had a significant positive impact on various aspects of Graves' orbitopathy. Over a period of six months, patients taking selenium showed a notable reduction in clinical activity scores, which reflect the severity of eye symptoms. Furthermore, their quality of life also improved significantly.
We observed improvements not only in the overall quality of life specific to eye conditions, but also in visual and psychological functioning scores. Additionally, selenium appeared to reduce the width of the eyelids, providing further benefits for eye-related symptoms. However, we found no significant changes in other areas, such as eye bulging or muscle movement abilities.
Importantly, selenium supplementation was deemed safe with minor side effects reported, suggesting it could be a viable option for managing Graves' orbitopathy. While our results are promising, we believe further research is needed to thoroughly validate the long-term effectiveness and safety of selenium treatment for this condition.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 38 Reviews
7
- All Reviews
- Positive Reviews
- Negative Reviews
9
Easier breathing
28 people found this helpful
Autoimmune disorder! I purchased this product at a great price. The small package fits in the palm of my hand and the quality appears satisfactory, with selenium and molybdenum in the ingredients. The capsules are of average size and easy to swallow. While the smell isn't pleasant, I believe it's due to the selenium. It effectively liquefies biofilms, mucus, and other pathogens, gently ridding the body of them. It strengthens my immune system, preventing illness at the first signs of trouble. After experiencing terrible shortness of breath due to my autoimmune disorder, this drug has significantly improved my ability to breathe! I highly recommend it!
Read More
8
Detoxification support
26 people found this helpful
N-acetylcysteine is an effective detoxification regulator that supports glutathione production, vital for eliminating toxins and maintaining a robust immune system. It helps combat free radicals, which, when accumulated, compromise immunity. This additive, rich in selenium and gluten-free, is remarkable, and I recommend it for overall well-being.
Read More
9
Reduced thyroid antibodies
8 people found this helpful
Initially, I thought NAC was for colds until I was recommended it for my autoimmune disorder (AIT). This supplement made it onto my treatment list. Glutathione deficiency correlates with raised thyroid antibodies. N-acetylcysteine converts to glutathione, helping to reduce those antibodies by neutralising hydrogen peroxide and supporting intestinal permeability and detoxification. I take three capsules (1800 mg) each morning with meals. I've been treatment for under a month, and my antibodies are starting to decrease!
Read More
9
Effective detoxification
6 people found this helpful
Excellent! As we age, the body's cleansing process slows down, making detoxification even more essential. The small-sized capsules are easy to swallow, and the first-order packaging is of high quality with protective seals. I've definitely felt the benefits; there’s a lightness in my body after using them. The taste is neutral.
Read More
10
Relieves symptoms
3 people found this helpful
Excellent! I purchased this for my brother, who has respiratory issues. He’s very pleased with the results. Thank you!
Read More
Frequently Asked Questions
9
Reduced thyroid antibodies
8 people found this helpful
Initially, I thought NAC was for colds until I was recommended it for my autoimmune disorder (AIT). This supplement made it onto my treatment list. Glutathione deficiency correlates with raised thyroid antibodies. N-acetylcysteine converts to glutathione, helping to reduce those antibodies by neutralising hydrogen peroxide and supporting intestinal permeability and detoxification. I take three capsules (1800 mg) each morning with meals. I've been treatment for under a month, and my antibodies are starting to decrease!
9
Joint pain relief
3 people found this helpful
I am re-ordering as I had noted excellent results with NAC. As I approached 40, my joint aches worsened over the years. After just a week of taking 2 NAC daily, my joint pain disappeared completely. Despite gym closures during covid, I jogged several miles weekly with no discomfort in my knees, hips, or feet. I will continue using it.
6
Reduced adhesions
91 people found this helpful
Diagnosed with severe endometriosis and extreme adhesions, I have been using NAC for ovarian cysts, endometriosis, and adhesions three times a day for over a year. Unfortunately, it did not affect my large cysts or unblock my ovary tube. However, my gynaecologist noted an improvement in my adhesions, and my endometriosis is stable now. Initially, I felt no change, but I later experienced unusual sensations in my belly. It was once very tight from adhesions, but now it feels normal. Although it does upset my stomach in the mornings, I find it bearable and the package arrived quickly in the Netherlands. I will order again.
9
Easier breathing
28 people found this helpful
Autoimmune disorder! I purchased this product at a great price. The small package fits in the palm of my hand and the quality appears satisfactory, with selenium and molybdenum in the ingredients. The capsules are of average size and easy to swallow. While the smell isn't pleasant, I believe it's due to the selenium. It effectively liquefies biofilms, mucus, and other pathogens, gently ridding the body of them. It strengthens my immune system, preventing illness at the first signs of trouble. After experiencing terrible shortness of breath due to my autoimmune disorder, this drug has significantly improved my ability to breathe! I highly recommend it!
9
Asthma improvement observed
2 people found this helpful
I adore this brand and product. Although I can't recall why I started NAC, I've witnessed a considerable enhancement in both my asthma and overall lung health since beginning it. My reliance on my inhaler has dissipated. I recommend this to everyone and am reordering another bottle.
7.5
Enhances communication
16 people found this helpful
I ordered this for my child with autism. It’s common knowledge among those affected by similar challenges that detoxification is crucial. After using this product for a month, I noticed a significant improvement in my child's meaningful interactions. Please like my review—it’s sincere!
7.5
Resolves congestion
24 people found this helpful
I've been taking glutathione with liposomal vitamin C and biotin for weeks. I was amazed by the skin-brightening effects of glutathione! Since adding NAC, I've noticed improved breathing—no nasal congestion while sleeping. My husband, who usually becomes drowsy after drinking, now stays alert, indicating better liver function.
9
Behaviour improvement noted
1 people found this helpful
I purchase this for my autistic son for glutathione support. It noticeably helps him, leading to improvements in his behaviour.
7.5
Detox benefits noted
4 people found this helpful
We always take it at the beginning of colds and coughs. We continue for about two weeks, even if the cold resolves in three days. NAC not only acts as a mucolytic but also has a detoxifying effect. The liver often requires support during colds and throughout recovery. It's an excellent product with numerous benefits. The dosage is 1 capsule twice daily before meals. Additionally, it aids considerably with alcohol intoxication. It's advised to take it before parties and again the next morning. Although I don’t drink, friends use it to support their liver and counteract hangover symptoms. If not ordered from iHerb, one can substitute it with a pharmacy ACC at a 600 mg dose. If this review was helpful, please like it.
9
We explored the effects of selenium supplements on patients with Hashimoto's thyroiditis, an autoimmune disorder that can affect thyroid function. Through a structured analysis of studies, we focused on how selenium could potentially lower the levels of thyroid autoantibodies.
Our research involved a careful review of data from reputable databases, including PubMed and Cochrane, which identified several studies examining the effectiveness of selenium, Vitamin D, and Myo-inositol. Among these, the results showed that selenium supplementation significantly reduced both thyroid peroxidase autoantibodies (TPOAb) and thyroglobulin autoantibodies (TgAb) when compared to a placebo group.
Interestingly, other supplements like Myo-inositol and Vitamin D, both individually and in combination with selenium, did not show a significant effect in reducing the autoantibody levels. Based on these findings, it appears that incorporating selenium into treatment regimens may offer a beneficial adjunct for those managing Hashimoto's thyroiditis.
Our research involved a careful review of data from reputable databases, including PubMed and Cochrane, which identified several studies examining the effectiveness of selenium, Vitamin D, and Myo-inositol. Among these, the results showed that selenium supplementation significantly reduced both thyroid peroxidase autoantibodies (TPOAb) and thyroglobulin autoantibodies (TgAb) when compared to a placebo group.
Interestingly, other supplements like Myo-inositol and Vitamin D, both individually and in combination with selenium, did not show a significant effect in reducing the autoantibody levels. Based on these findings, it appears that incorporating selenium into treatment regimens may offer a beneficial adjunct for those managing Hashimoto's thyroiditis.
7
Saccharomyces cerevisiae shows immune modulation
We explored how ABBi16, a blend of β-glucans from Saccharomyces cerevisiae, impacts immune responses in the context of autoimmune conditions. Our findings indicate that ABBi16 effectively promotes Th1 responses while increasing IL-10 and IL-22 secretion, contributing to a balanced immune response. Notably, this compound did not trigger IL-17 production, which is an inflammatory marker, suggesting that it is a safe oral supplement for those with autoimmune disorders. Overall, ABBi16 shows promise in promoting a more regulated immune system.
9
We investigated the role of certain yeast polysaccharides in modulating immune responses related to autoimmune disorders. Our focus was on mannan/β-1,6-glucan-containing polysaccharides (MGCP), which showed strong anti-inflammatory properties.
MGCP prompted the development of regulatory T cells and reduced harmful immune responses in models of inflammatory diseases. While we saw promising results in laboratory settings, these findings emphasize the potential of using yeast-derived compounds for therapeutic approaches in treating autoimmune conditions.
MGCP prompted the development of regulatory T cells and reduced harmful immune responses in models of inflammatory diseases. While we saw promising results in laboratory settings, these findings emphasize the potential of using yeast-derived compounds for therapeutic approaches in treating autoimmune conditions.
0
We aimed to explore how selenium affects autoimmune thyroid disease (AITD), specifically looking at three conditions: autoimmune thyroiditis (AIT), autoimmune hyperthyroidism (AIH), and Graves' disease (GD). Using a research method called Mendelian randomization, we analyzed genetic data to establish potential causal links between selenium levels and these autoimmune disorders.
Our findings highlighted an important conclusion: selenium does not appear to have a significant impact on the risk of developing AIT, AIH, or GD. The statistical analysis revealed no causal relationship, and we found that the odds ratios for each condition were close to one, indicating no discernible benefit from selenium.
Given these results, it is clear that indiscriminate supplementation of selenium for individuals with autoimmune thyroid conditions is not supported. Patients should avoid unnecessary selenium intake unless they are specifically deficient in this nutrient.
Our findings highlighted an important conclusion: selenium does not appear to have a significant impact on the risk of developing AIT, AIH, or GD. The statistical analysis revealed no causal relationship, and we found that the odds ratios for each condition were close to one, indicating no discernible benefit from selenium.
Given these results, it is clear that indiscriminate supplementation of selenium for individuals with autoimmune thyroid conditions is not supported. Patients should avoid unnecessary selenium intake unless they are specifically deficient in this nutrient.
References
- Tian C, Yan M, Guo J, Zhou Y, Du B, et al. Yeast Cell Wall-Mediated Ileal Targeted Delivery System for IgA Nepharopathy Therapy. ACS Biomater Sci Eng. 2025;11:1498. 10.1021/acsbiomaterials.4c01941
- Vuscan P, Röring RJ, Kischkel B, Tintoré M, Cuñé J, et al. Effect of Saccharomyces cerevisiae β-glucan on the T helper cytokine profile. Cytokine. 2025;187:156871. 10.1016/j.cyto.2025.156871
- Lee C, Verma R, Byun S, Jeun EJ, Kim GC, et al. Structural specificities of cell surface β-glucan polysaccharides determine commensal yeast mediated immuno-modulatory activities. Nat Commun. 2021;12:3611. 10.1038/s41467-021-23929-9
- de Campos Fraga-Silva TF, Mimura LAN, de Oliveira LRC, Dos Santos Toledo JH, Borim PA, et al. Selenization of S. cerevisiae increases its protective potential in experimental autoimmune encephalomyelitis by triggering an intestinal immunomodulatory loop. Sci Rep. 2020;10:22190. 10.1038/s41598-020-79102-7
- Alvarez P, Augustín JJ, Tamayo E, Iglesias M, Acinas O, et al. Therapeutic Effects of Anti-Bone Morphogenetic Protein and Activin Membrane-Bound Inhibitor Treatment in Psoriasis and Arthritis. Arthritis Rheumatol. 2020;72:1547. 10.1002/art.41272
- Aboud C, Zamaria N, Cannistrà C. Treatment of hidradenitis suppurativa: Surgery and yeast (Saccharomyces cerevisiae)-exclusion diet. Results after 6 years. Surgery. 2020;167:1012. 10.1016/j.surg.2019.12.015
- Souza LSL, Campos RO, Braga JS, Jesus JDS, Ramos HE, et al. Selenium nutritional status and thyroid dysfunction. Arch Endocrinol Metab. 2025;69:e230348. 10.20945/2359-4292-2023-0348
- Wang Q, Wu Y, Ouyang L, Min X, Zheng M, et al. Single-cell analyses of intestinal epithelium reveal the dysregulation of gut immune microenvironment in systemic lupus erythematosus. J Transl Med. 2025;23:118. 10.1186/s12967-025-06147-5
- Peng B, Wang W, Gu Q, Wang P, Teng W, et al. Effects of different supplements on Hashimoto's thyroiditis: a systematic review and network meta-analysis. Front Endocrinol (Lausanne). 2024;15:1445878. 10.3389/fendo.2024.1445878
- Wahl L, Samson Chillon T, Seemann P, Ohrndorf S, Ochwadt R, et al. Serum selenium, selenoprotein P and glutathione peroxidase 3 in rheumatoid, psoriatic, juvenile idiopathic arthritis, and osteoarthritis. J Nutr Biochem. 2025;135:109776. 10.1016/j.jnutbio.2024.109776
- Sharabati I, Qafesha RM, Hindawi MD, Amro S, Ayesh BM. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials. Clin Endocrinol (Oxf). 2024;101:669. 10.1111/cen.15128
- Chung CW, Kim K, Park SK, Ju DL, Park YJ, et al. Selenium levels and their association with thyroid autoimmunity and severe preeclampsia in pregnancy: Insights from a prospective ideal breast milk cohort study. Eur Thyroid J. 2024;13. 10.1530/ETJ-24-0007
- Hu C, Yu YF, Tong KK, Hu G, Wu JY, et al. A Mendelian randomization study of the effect of selenium on autoimmune thyroid disease. Eur Rev Med Pharmacol Sci. 2024;28:2988. 10.26355/eurrev_202404_36011
- Khalil DY, Hussein RH, El-Kholy WM. Mesenchymal Stem Cell-Derived Exosomes Loaded with Selenium or Nano Selenium as a Novel Therapeutic Paradigm for Streptozotocin-Induced Type 1 Diabetes in Rats. Biology (Basel). 2024;13. 10.3390/biology13040253
- Potita P, Pruksakorn V, Srichomkwun P, Kingpetch K, Saonanon P. Selenium supplementation in inactive moderate to severe Graves' orbitopathy patients: a randomized controlled trial. Orbit. 2024;43:329. 10.1080/01676830.2024.2315566
- Duntas LH. Reassessing Selenium for the Management of Hashimoto's Thyroiditis: The Selini Shines Bright for Autoimmune Thyroiditis Patients. Thyroid. 2024;34:292. 10.1089/thy.2024.0078
- Wang S, Chen P, He Y, Wei J, Tian L, et al. A follow-up study on factors affecting the recovery of patients with hypothyroidism in different selenium environments. BMC Endocr Disord. 2024;24:14. 10.1186/s12902-024-01536-1
- Huwiler VV, Maissen-Abgottspon S, Stanga Z, Mühlebach S, Trepp R, et al. Selenium Supplementation in Patients with Hashimoto Thyroiditis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Thyroid. 2024;34:295. 10.1089/thy.2023.0556
- Wang C, Qiao J, Liu S, Piao S, Zhou Y, et al. Selenium in the treatment of mild-to-moderate Graves' orbitopathy: a 5-year prospective controlled cohort study. Endocrine. 2024;84:1072. 10.1007/s12020-023-03672-5
- Yavari M, Akbari M, Ramezani Ahmadi A, Siavash Dastjerdi M, Hashemi MS. Investigating the effect of combined use of selenium and Myo-inositol supplements on thyroid function and autoimmune characteristics in thyroid disorders: a systematic review and meta-analysis. Expert Rev Endocrinol Metab. 2024;19:269. 10.1080/17446651.2023.2295487
- Foos W, Maliakkal Hernandez J, Mansour TN. Selenium supplementation in thyroid eye disease: an updated review from a clinical ophthalmic perspective. Orbit. 2024;43:790. 10.1080/01676830.2023.2276783
- Rezaeimanesh N, Rafiee P, Saeedi R, Khosravian P, Sahraian MA, et al. The effect of crocin-selenium nanoparticles on the cognition and oxidative stress markers of multiple sclerosis patients: a randomized triple-blinded placebo-controlled clinical trial. Biometals. 2024;37:305. 10.1007/s10534-023-00548-z
- Chen X, Yang Y, Chen J, He Y, Huang Y, et al. Dual-driven selenium Janus single-atom nanomotors for autonomous regulating mitochondrial oxygen imbalance to catalytic therapy of rheumatoid arthritis. Redox Biol. 2025;81:103574. 10.1016/j.redox.2025.103574
