SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.3
USERS' SCORE
Moderately Good
Based on 38 Reviews
7.7
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Selenium (from SelenoExcell® High Selenium Yeast) (Saccharomyces cerevisiae)
50 mcg
90%
Molybdenum (from molybdenum glycinate chelate)
50 mcg
110%
N-Acetylcysteine (NAC)
600 mg
†
Top Medical Research Studies
9
Selenium aids Graves' orbitopathy treatment
The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
Directly addresses selenium's effects
We explored how selenium supplementation might help individuals suffering from Graves' orbitopathy, an autoimmune disorder linked to thyroid dysfunction. Our approach involved a systematic review and meta-analysis that assessed results from four randomized controlled trials.
The findings revealed that selenium supplementation had a significant positive impact on various aspects of Graves' orbitopathy. Over a period of six months, patients taking selenium showed a notable reduction in clinical activity scores, which reflect the severity of eye symptoms. Furthermore, their quality of life also improved significantly.
We observed improvements not only in the overall quality of life specific to eye conditions, but also in visual and psychological functioning scores. Additionally, selenium appeared to reduce the width of the eyelids, providing further benefits for eye-related symptoms. However, we found no significant changes in other areas, such as eye bulging or muscle movement abilities.
Importantly, selenium supplementation was deemed safe with minor side effects reported, suggesting it could be a viable option for managing Graves' orbitopathy. While our results are promising, we believe further research is needed to thoroughly validate the long-term effectiveness and safety of selenium treatment for this condition.
The findings revealed that selenium supplementation had a significant positive impact on various aspects of Graves' orbitopathy. Over a period of six months, patients taking selenium showed a notable reduction in clinical activity scores, which reflect the severity of eye symptoms. Furthermore, their quality of life also improved significantly.
We observed improvements not only in the overall quality of life specific to eye conditions, but also in visual and psychological functioning scores. Additionally, selenium appeared to reduce the width of the eyelids, providing further benefits for eye-related symptoms. However, we found no significant changes in other areas, such as eye bulging or muscle movement abilities.
Importantly, selenium supplementation was deemed safe with minor side effects reported, suggesting it could be a viable option for managing Graves' orbitopathy. While our results are promising, we believe further research is needed to thoroughly validate the long-term effectiveness and safety of selenium treatment for this condition.
Read More
0
Selenium supplementation ineffective for AITD
A Mendelian randomization study of the effect of selenium on autoimmune thyroid disease.
Directly assesses selenium's effect
We aimed to explore how selenium affects autoimmune thyroid disease (AITD), specifically looking at three conditions: autoimmune thyroiditis (AIT), autoimmune hyperthyroidism (AIH), and Graves' disease (GD). Using a research method called Mendelian randomization, we analyzed genetic data to establish potential causal links between selenium levels and these autoimmune disorders.
Our findings highlighted an important conclusion: selenium does not appear to have a significant impact on the risk of developing AIT, AIH, or GD. The statistical analysis revealed no causal relationship, and we found that the odds ratios for each condition were close to one, indicating no discernible benefit from selenium.
Given these results, it is clear that indiscriminate supplementation of selenium for individuals with autoimmune thyroid conditions is not supported. Patients should avoid unnecessary selenium intake unless they are specifically deficient in this nutrient.
Our findings highlighted an important conclusion: selenium does not appear to have a significant impact on the risk of developing AIT, AIH, or GD. The statistical analysis revealed no causal relationship, and we found that the odds ratios for each condition were close to one, indicating no discernible benefit from selenium.
Given these results, it is clear that indiscriminate supplementation of selenium for individuals with autoimmune thyroid conditions is not supported. Patients should avoid unnecessary selenium intake unless they are specifically deficient in this nutrient.
Read More
9
Selenium reduces thyroid autoantibodies
Effects of different supplements on Hashimoto's thyroiditis: a systematic review and network meta-analysis.
High relevance to autoimmune research
We explored the effects of selenium supplements on patients with Hashimoto's thyroiditis, an autoimmune disorder that can affect thyroid function. Through a structured analysis of studies, we focused on how selenium could potentially lower the levels of thyroid autoantibodies.
Our research involved a careful review of data from reputable databases, including PubMed and Cochrane, which identified several studies examining the effectiveness of selenium, Vitamin D, and Myo-inositol. Among these, the results showed that selenium supplementation significantly reduced both thyroid peroxidase autoantibodies (TPOAb) and thyroglobulin autoantibodies (TgAb) when compared to a placebo group.
Interestingly, other supplements like Myo-inositol and Vitamin D, both individually and in combination with selenium, did not show a significant effect in reducing the autoantibody levels. Based on these findings, it appears that incorporating selenium into treatment regimens may offer a beneficial adjunct for those managing Hashimoto's thyroiditis.
Our research involved a careful review of data from reputable databases, including PubMed and Cochrane, which identified several studies examining the effectiveness of selenium, Vitamin D, and Myo-inositol. Among these, the results showed that selenium supplementation significantly reduced both thyroid peroxidase autoantibodies (TPOAb) and thyroglobulin autoantibodies (TgAb) when compared to a placebo group.
Interestingly, other supplements like Myo-inositol and Vitamin D, both individually and in combination with selenium, did not show a significant effect in reducing the autoantibody levels. Based on these findings, it appears that incorporating selenium into treatment regimens may offer a beneficial adjunct for those managing Hashimoto's thyroiditis.
Read More
Most Useful Reviews
9.5
Easier breathing
Autoimmune disorder! I purchased this product at a great price. The small package fits in the palm of my hand and the quality appears satisfactory, with selenium and molybdenum in the ingredients. The capsules are of average size and easy to swallow. While the smell isn't pleasant, I believe it's due to the selenium. It effectively liquefies biofilms, mucus, and other pathogens, gently ridding the body of them. It strengthens my immune system, preventing illness at the first signs of trouble. After experiencing terrible shortness of breath due to my autoimmune disorder, this drug has significantly improved my ability to breathe! I highly recommend it!
Read More
9
Detoxification support
N-acetylcysteine is an effective detoxification regulator that supports glutathione production, vital for eliminating toxins and maintaining a robust immune system. It helps combat free radicals, which, when accumulated, compromise immunity. This additive, rich in selenium and gluten-free, is remarkable, and I recommend it for overall well-being.
Read More
8.3
Reduced thyroid antibodies
Initially, I thought NAC was for colds until I was recommended it for my autoimmune disorder (AIT). This supplement made it onto my treatment list. Glutathione deficiency correlates with raised thyroid antibodies. N-acetylcysteine converts to glutathione, helping to reduce those antibodies by neutralising hydrogen peroxide and supporting intestinal permeability and detoxification. I take three capsules (1800 mg) each morning with meals. I've been treatment for under a month, and my antibodies are starting to decrease!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.3
- All Researches
9
Effective IgA nephropathy treatment method
Yeast Cell Wall-Mediated Ileal Targeted Delivery System for IgA Nepharopathy Therapy.
Highly relevant therapeutic breakthrough
We explored a novel oral drug delivery system designed specifically for treating IgA nephropathy, an autoimmune disorder. Using hydroxychloroquine and dexamethasone paired with yeast cell walls, we aimed for targeted delivery to the ileal region.
Our findings revealed that this system effectively reduced harmful IgA levels and improved kidney tissue health in test subjects. We also noted significant reductions in inflammatory markers, suggesting potential benefits in managing IgA nephropathy through this innovative approach.
Our findings revealed that this system effectively reduced harmful IgA levels and improved kidney tissue health in test subjects. We also noted significant reductions in inflammatory markers, suggesting potential benefits in managing IgA nephropathy through this innovative approach.
Read More
9
Yeast polysaccharides may reduce inflammation
Structural specificities of cell surface β-glucan polysaccharides determine commensal yeast mediated immuno-modulatory activities.
Highly relevant to autoimmune treatment
We investigated the role of certain yeast polysaccharides in modulating immune responses related to autoimmune disorders. Our focus was on mannan/β-1,6-glucan-containing polysaccharides (MGCP), which showed strong anti-inflammatory properties.
MGCP prompted the development of regulatory T cells and reduced harmful immune responses in models of inflammatory diseases. While we saw promising results in laboratory settings, these findings emphasize the potential of using yeast-derived compounds for therapeutic approaches in treating autoimmune conditions.
MGCP prompted the development of regulatory T cells and reduced harmful immune responses in models of inflammatory diseases. While we saw promising results in laboratory settings, these findings emphasize the potential of using yeast-derived compounds for therapeutic approaches in treating autoimmune conditions.
Read More
9
Effective anti-BAMBI treatment in mice
Therapeutic Effects of Anti-Bone Morphogenetic Protein and Activin Membrane-Bound Inhibitor Treatment in Psoriasis and Arthritis.
High relevance for autoimmune therapy
We investigated the effects of a novel treatment targeting BAMBI, a protein involved in immune cell regulation, on autoimmune disorders like psoriasis and arthritis in mice. Through careful experimentation with control groups, we found that the anti-BAMBI antibody significantly increased protective Treg cells and reduced disease progression in various models. This treatment effectively prevented skin psoriasis and type II collagen-induced arthritis, hinting at new therapeutic possibilities for chronic inflammatory conditions driven by immune system dysfunction.
Read More
9
Selenium reduces thyroid autoantibodies
Effects of different supplements on Hashimoto's thyroiditis: a systematic review and network meta-analysis.
High relevance to autoimmune research
We explored the effects of selenium supplements on patients with Hashimoto's thyroiditis, an autoimmune disorder that can affect thyroid function. Through a structured analysis of studies, we focused on how selenium could potentially lower the levels of thyroid autoantibodies.
Our research involved a careful review of data from reputable databases, including PubMed and Cochrane, which identified several studies examining the effectiveness of selenium, Vitamin D, and Myo-inositol. Among these, the results showed that selenium supplementation significantly reduced both thyroid peroxidase autoantibodies (TPOAb) and thyroglobulin autoantibodies (TgAb) when compared to a placebo group.
Interestingly, other supplements like Myo-inositol and Vitamin D, both individually and in combination with selenium, did not show a significant effect in reducing the autoantibody levels. Based on these findings, it appears that incorporating selenium into treatment regimens may offer a beneficial adjunct for those managing Hashimoto's thyroiditis.
Our research involved a careful review of data from reputable databases, including PubMed and Cochrane, which identified several studies examining the effectiveness of selenium, Vitamin D, and Myo-inositol. Among these, the results showed that selenium supplementation significantly reduced both thyroid peroxidase autoantibodies (TPOAb) and thyroglobulin autoantibodies (TgAb) when compared to a placebo group.
Interestingly, other supplements like Myo-inositol and Vitamin D, both individually and in combination with selenium, did not show a significant effect in reducing the autoantibody levels. Based on these findings, it appears that incorporating selenium into treatment regimens may offer a beneficial adjunct for those managing Hashimoto's thyroiditis.
Read More
9
Selenium aids Graves' orbitopathy treatment
The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
Directly addresses selenium's effects
We explored how selenium supplementation might help individuals suffering from Graves' orbitopathy, an autoimmune disorder linked to thyroid dysfunction. Our approach involved a systematic review and meta-analysis that assessed results from four randomized controlled trials.
The findings revealed that selenium supplementation had a significant positive impact on various aspects of Graves' orbitopathy. Over a period of six months, patients taking selenium showed a notable reduction in clinical activity scores, which reflect the severity of eye symptoms. Furthermore, their quality of life also improved significantly.
We observed improvements not only in the overall quality of life specific to eye conditions, but also in visual and psychological functioning scores. Additionally, selenium appeared to reduce the width of the eyelids, providing further benefits for eye-related symptoms. However, we found no significant changes in other areas, such as eye bulging or muscle movement abilities.
Importantly, selenium supplementation was deemed safe with minor side effects reported, suggesting it could be a viable option for managing Graves' orbitopathy. While our results are promising, we believe further research is needed to thoroughly validate the long-term effectiveness and safety of selenium treatment for this condition.
The findings revealed that selenium supplementation had a significant positive impact on various aspects of Graves' orbitopathy. Over a period of six months, patients taking selenium showed a notable reduction in clinical activity scores, which reflect the severity of eye symptoms. Furthermore, their quality of life also improved significantly.
We observed improvements not only in the overall quality of life specific to eye conditions, but also in visual and psychological functioning scores. Additionally, selenium appeared to reduce the width of the eyelids, providing further benefits for eye-related symptoms. However, we found no significant changes in other areas, such as eye bulging or muscle movement abilities.
Importantly, selenium supplementation was deemed safe with minor side effects reported, suggesting it could be a viable option for managing Graves' orbitopathy. While our results are promising, we believe further research is needed to thoroughly validate the long-term effectiveness and safety of selenium treatment for this condition.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 38 Reviews
7.7
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Easier breathing
Autoimmune disorder! I purchased this product at a great price. The small package fits in the palm of my hand and the quality appears satisfactory, with selenium and molybdenum in the ingredients. The capsules are of average size and easy to swallow. While the smell isn't pleasant, I believe it's due to the selenium. It effectively liquefies biofilms, mucus, and other pathogens, gently ridding the body of them. It strengthens my immune system, preventing illness at the first signs of trouble. After experiencing terrible shortness of breath due to my autoimmune disorder, this drug has significantly improved my ability to breathe! I highly recommend it!
Read More
9
Detoxification support
N-acetylcysteine is an effective detoxification regulator that supports glutathione production, vital for eliminating toxins and maintaining a robust immune system. It helps combat free radicals, which, when accumulated, compromise immunity. This additive, rich in selenium and gluten-free, is remarkable, and I recommend it for overall well-being.
Read More
8.3
Reduced thyroid antibodies
Initially, I thought NAC was for colds until I was recommended it for my autoimmune disorder (AIT). This supplement made it onto my treatment list. Glutathione deficiency correlates with raised thyroid antibodies. N-acetylcysteine converts to glutathione, helping to reduce those antibodies by neutralising hydrogen peroxide and supporting intestinal permeability and detoxification. I take three capsules (1800 mg) each morning with meals. I've been treatment for under a month, and my antibodies are starting to decrease!
Read More
9.5
Effective detoxification
Excellent! As we age, the body's cleansing process slows down, making detoxification even more essential. The small-sized capsules are easy to swallow, and the first-order packaging is of high quality with protective seals. I've definitely felt the benefits; there’s a lightness in my body after using them. The taste is neutral.
Read More
10
Relieves symptoms
Excellent! I purchased this for my brother, who has respiratory issues. He’s very pleased with the results. Thank you!
Frequently Asked Questions
No FAQs are available for this product and symptom.
